Publications

A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression

Workman RE, Pammi T, Nguyen BTK, Graeff LW, Smith E, Sebald SM, Stoltzfus MJ, Modell JW. bioRxiv. 2020 May 21. doi:10.1101/2020.05.21.102756

bioRxiv

CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

Modell JW, Jiang W, Marraffini LA. Nature. 2017 Apr 6. doi:10.1038/nature21719

Full text

Cas9 specifies functional viral targets during CRISPR–Cas adaptation

Heler R, Samai P, Modell JW, Weiner C, Goldberg GW, Bikard D, Marraffini LA. Nature. 2015 Mar 12. doi:10.1038/nature14245pbio.1001977

Full text

A DNA damage-induced, SOS-independent checkpoint regulates cell division in Caulobacter crescentus

Modell JW, Kambara TK, Perchuk BS, Laub MT. PLoS Biology. 2014 Oct 28. doi:10.1371/journal.pbio.1001977

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A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW

Modell JW, Hopkins AC, Laub MT. Genes and Development. 2011 Jun 15. doi:10.1101/gad.2038911

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Johns Hopkins School of Medicine

Department of Molecular Biology and Genetics

©2019 by Modell Lab

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